Pharmaceutics and Drug Delivery System

Pharmaceutical/drug products, in the form in which they are marketed for use, typically involve a mixture of active drug components and non-drug components, along with other non-reusable material.  Depending on the context, multiple unit dose can refer to distinct drug products, or it can also sometimes refer specifically to the chemical formulation of a drug product’s constituent drug substances and any blends involved.  A crude drug is the substance, obtained from plants or animals, and used to cure, treat, restore an efficient health state, or optimize a curing function.  Dosage form is the crude drug in its final form, after particular characteristics have been added  to it. The drug manufacturing includes addition of additives, i.e., pharmaceutical ingredients.  The additives are mainly non-medicinal substances used for many purposes. They are added to enhance drug form, quality, efficacy for various purposes including but not limited to: solubilizing agents, for dilution, as emulsifying agents, as thickeners, as stabilizers, as preservatives, as coloring agents, as flavoring agents, and so on.  Dosage forms are also the effective means by which drug molecules reach the target site inside the body, to provide their mechanism of actions.  From the drug manufacturing processes, we can conclude the importance of dosage forms for their great necessity in ensuring:

– Optimal action of the drug

– Accurate dose is administered

– Biocompatibility,bioaffinity, absorption

– Protection from gastric juice

– The drug stability against atmospheric conditions to avoid oxidation or destruction and controlled release.

– A long shelf life for the drug

– Masking unpalatable taste or unpleasant odor

– Sustained or controlled release of the medication

– etc.

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