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Nano/micro Surface Treatments

Nano/micro Surface Treatments

Researchers work on proprietary particle coating and surface treatment technology to tailor the surface properties of the nanoparticles. By discreetly encapsulating individual particles with various chemical and physical processes, they are able to meet a customer’s performance requirements by controlling the particle size distribution, ensuring compatibility with the customer’s formulation, and including beneficial additives to control pH or rheology, to name a few.  In most instances, it is beneficial to mediate the interface between the nanoparticle surface and the application matrix in which the nanoparticles are to be utilized.  For example, for a naturally hydrophilic nanoparticle to be used effectively in non-polar media such as cosmetic oils, the surface of the particle may need to be rendered hydrophobic for uniform dispersion, compatibility, and performance.  The proprietary chemistry and process technology used to prepare these dispersions ensures that the customers receive ready-to-use products in which the nanoparticles are stabilized at their primary particle size, with no secondary structure or agglomeration.  The purpose to develop an optimized process is to impart a wide range of functionality to the particles, which not only ensures the success in the application but also provides the required flexibility in formulation with their nanoparticles.  The effectiveness of these surface treatment and coating processes can be examined, verified and optimized with our precision instruments such as OCA, DCAT, ODG and T-100 on the produced particle samples in either dry powder or pre-dispersed format.

Our devices which can help you: OCA15, OCA25, OCA50, DCAT11, DCAT21, ODG, T100

Cleaning Processes Optimization and Validation

Cleaning Processes Optimization and Validation

There is a tremendous amount of types of industrial parts and surfaces required for cleaning before they become a finished product for users.  All the relevant processes or procedures to respond to the required cleanliness, whether they are chemical or physical methods will be interested in the effectiveness of their cleaning processes and cleaning formulations. The industry which is involved in cleaning process is widespread.

  • Cleaning equipment systems and cleaning reagents for
    1. wet cleaning processes
    2. thermal processes
    3. blasting processes
    4. special processes
    5. mechanical processes
  • Systems for drying processes will need to check on water stains or chemical leftover
  • Processes and systems for corrosion protection and preservation
  • Reagents for corrosion protection and preservation
  • Processes and systems for quality assurance
  • Clean room systems
  • Surface treatment systems
  • Processes and techniques in recycling and disposal
  • Components for cleaning systems
  • On-line automation cleaning systems
  • Cleaning products

SITA CleanoSpector, SITA ConSpector, SITA Cleanline ST, SITA Cleanline CL for direct cleanliness validation and the Dataphysics OCA devices for contact angle measuring are all available for both batch and on-line cleanliness checking to help you maintain and optimize your cleaning requirements.

Pharmaceutics and Drug Delivery System

Pharmaceutics and Drug Delivery System

Pharmaceutical/drug products, in the form in which they are marketed for use, typically involve a mixture of active drug components and non-drug components, along with other non-reusable material.  Depending on the context, multiple unit dose can refer to distinct drug products, or it can also sometimes refer specifically to the chemical formulation of a drug product’s constituent drug substances and any blends involved.  A crude drug is the substance, obtained from plants or animals, and used to cure, treat, restore an efficient health state, or optimize a curing function.  Dosage form is the crude drug in its final form, after particular characteristics have been added  to it. The drug manufacturing includes addition of additives, i.e., pharmaceutical ingredients.  The additives are mainly non-medicinal substances used for many purposes. They are added to enhance drug form, quality, efficacy for various purposes including but not limited to: solubilizing agents, for dilution, as emulsifying agents, as thickeners, as stabilizers, as preservatives, as coloring agents, as flavoring agents, and so on.  Dosage forms are also the effective means by which drug molecules reach the target site inside the body, to provide their mechanism of actions.  From the drug manufacturing processes, we can conclude the importance of dosage forms for their great necessity in ensuring:

– Optimal action of the drug

– Accurate dose is administered

– Biocompatibility

– Protection from gastric juice

– The drug stability against atmospheric conditions to avoid oxidation or destruction

– A long shelf life for the drug

– Masking unpalatable taste or unpleasant odor

– Sustained or controlled release of the medication

– etc.

 

Our devices which can help: DCAT, OCAs, SVT20, T100, etc.